Nikolai V Ravin Selected Research

Human Influenza (Influenza)

1/2022	Nanoparticles based on artificial self-assembling peptide and displaying M2e peptide and stalk HA epitopes of influenza A virus induce potent humoral and T-cell responses and protect against the viral infection.
1/2020	Plant-Produced Recombinant Influenza A Virus Candidate Vaccine Based on Flagellin Linked to Conservative Fragments of M2 Protein and Hemagglutintin.
12/2019	Rapid High-Yield Transient Expression of Swine Hepatitis E ORF2 Capsid Proteins in Nicotiana benthamiana Plants and Production of Chimeric Hepatitis E Virus-Like Particles Bearing the M2e Influenza Epitope.
4/2018	Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes.
1/2018	Combination of M2e peptide with stalk HA epitopes of influenza A virus enhances protective properties of recombinant vaccine.
1/2018	Plant-produced Recombinant Influenza A Vaccines Based on the M2e Peptide.
1/2016	High immunogenicity of plant-produced candidate influenza vaccine based on the M2e peptide fused to flagellin.
6/2015	Development of a candidate influenza vaccine based on virus-like particles displaying influenza M2e peptide into the immunodominant loop region of hepatitis B core antigen: Insertion of multiple copies of M2e increases immunogenicity and protective efficiency.
6/2015	Development of a candidate influenza vaccine based on virus-like particles displaying influenza M2e peptide into the immunodominant region of hepatitis B core antigen: Broad protective efficacy of particles carrying four copies of M2e.
5/2015	Rapid high-yield expression of a candidate influenza vaccine based on the ectodomain of M2 protein linked to flagellin in plants using viral vectors.

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Nikolai V Ravin Research Topics

Disease

12	Human Influenza (Influenza) 01/2022 - 01/2013
8	Infections 04/2018 - 04/2003
2	Hepatitis E 11/2020 - 12/2019
2	Influenza in Birds (Avian Flu) 06/2015 - 01/2015
1	Virus Diseases (Viral Diseases) 01/2022
1	Autism Spectrum Disorder 12/2021
1	Iron Deficiencies 12/2021
1	COVID-19 12/2021
1	Polyploidy 11/2017
1	Cysts 01/2016
1	Tuberculosis (Tuberculoses) 01/2013
1	Hypoxia (Hypoxemia) 08/2008

Drug/Important Bio-Agent (IBA)

10	VaccinesIBA 01/2022 - 01/2015
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2013
7	Peptides (Polypeptides)IBA 01/2022 - 01/2015
6	DNA (Deoxyribonucleic Acid)IBA 02/2015 - 04/2003
4	Influenza Vaccines (Influenza Vaccine)FDA Link 04/2018 - 06/2015
3	Hemagglutinins (Hemagglutinin)IBA 01/2022 - 01/2018
2	EpitopesIBA 01/2022 - 12/2019
2	Synthetic Vaccines (Recombinant Vaccines)IBA 12/2021 - 01/2018
2	FlagellinIBA 04/2018 - 01/2015
2	Hepatitis B Core AntigensIBA 06/2015 - 06/2015
2	EnzymesIBA 02/2015 - 03/2011
1	pyriteIBA 12/2021
1	greigiteIBA 12/2021
1	IronIBA 12/2021
1	Capsid Proteins (Capsid Protein)IBA 12/2019
1	AntigensIBA 04/2018
1	CytokinesIBA 04/2018
1	Surface Antigens (Surface Antigen)IBA 01/2018
1	Ribosomal DNA (rDNA)IBA 11/2017
1	5S Ribosomal RNAIBA 11/2017
1	LipidsIBA 01/2016
1	Immunodominant EpitopesIBA 06/2015
1	Recombinases (Recombinase)IBA 02/2015
1	Tyrosine (L-Tyrosine)FDA Link 02/2015
1	Recombinant ProteinsIBA 01/2015
1	Pharmaceutical PreparationsIBA 01/2013
1	Messenger RNA (mRNA)IBA 08/2008
1	5' Untranslated Regions (5' UTR)IBA 08/2008